Georges Patricia, Legault Jean, Lavoie Serge, Grenon Carole et Pichette André. (2012). Diterpenoids from the buds of Pinus banksiana Lamb. Molecules, 17, (8), p. 9716-9727.
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URL officielle: http://dx.doi.org/doi:10.3390/molecules17089716
Résumé
Three new diterpenoids, namely 7α-hydroxyabieta-8,11,13,15-tetraen-18-oic acid, 7β,15,18-trihydroxyabieta-8,11,13-triene, 13,15-dihydroxypodocarpa-8,11,13-triene, and 12 other known compounds were isolated from buds of Pinus banksiana Lamb. All these compounds, except for 7-oxodehydroabietinol, were isolated for the first time from this plant. Their structures were elucidated by detailed spectroscopic studies and comparison with published data. All isolated compounds were tested for cytotoxic and antibacterial activities. Overall, two compounds, 7-oxodehydroabietinol and 18-nor-4,15-dihydroxyabieta-8,11,13-trien-7-one, showed moderate cytotoxicity against a human lung carcinoma cell line.
| Type de document: | Article publié dans une revue avec comité d'évaluation |
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| ISSN: | 1420-3049 |
| Volume: | 17 |
| Numéro: | 8 |
| Pages: | p. 9716-9727 |
| Version évaluée par les pairs: | Oui |
| Date: | 2012 |
| Identifiant unique: | 10.3390/molecules17089716 |
| Sujets: | Sciences naturelles et génie > Sciences naturelles > Biologie et autres sciences connexes Sciences naturelles et génie > Sciences naturelles > Chimie |
| Département, module, service et unité de recherche: | Départements et modules > Département des sciences fondamentales |
| Mots-clés: | Pinus banksiana, bud, dehydroabietane, cytotoxicity, antibacterial activity |
| Déposé le: | 01 sept. 2021 18:18 |
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| Dernière modification: | 01 sept. 2021 18:18 |
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