Mulkijanyan Karen, Novikova Z., Sulakvelidze M., Getia M., Mshvildadze Vakhtang et Dekanosidze G. E.. (2013). Ivy water extracts as gastric ulcer preventive agents. Georgian medical news, 224, (11), p. 63-66.
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Résumé
In folk medicine the ivies (Hedera L. Fam.Araliaceae) are known as plants possessing diverse curative properties. A comparative phytochemical study of the biologically active water extracts of H. colchica and H. helix and evaluation of their ulcer preventive efficacy in ethanol-induced ulcer model in rats was carried out. Water extracts of H. colchica and H. helix (300 mg/kg, i.p.) significantly (p<0.01) decrease the ulcer index (0.50 and 1.38 vs 3.17 in control) and rise macroscopic curative ratio (84.2% and 56.6%, respectively). The results clearly indicate that pretreatment with water extract of H. colchica is preferable and further experiments are required to isolate the active principals responsible for itsantiulcerogenic activity.
| Type de document: | Article publié dans une revue avec comité d'évaluation |
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| Volume: | 224 |
| Numéro: | 11 |
| Pages: | p. 63-66 |
| Version évaluée par les pairs: | Oui |
| Date: | 2013 |
| Sujets: | Sciences naturelles et génie > Sciences naturelles > Biologie et autres sciences connexes Sciences naturelles et génie > Sciences naturelles > Chimie Sciences de la santé > Sciences médicales > Pharmacologie |
| Département, module, service et unité de recherche: | Départements et modules > Département des sciences fondamentales Unités de recherche > Centre de recherche sur la Boréalie (CREB) |
| Mots-clés: | animal, chemically induced disorder, chemistry, ethanol-induced ulcer, Hedera colchica, Hédera helix, human, ivy, male, pathology, plant leaf, rat, stomach ulcer, ulcer prevention, water extracts |
| Déposé le: | 07 juin 2023 14:55 |
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| Dernière modification: | 17 juill. 2023 19:34 |
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